(19)
(11) EP 1 848 825 A2

(12)

(43) Date of publication:
31.10.2007 Bulletin 2007/44

(21) Application number: 06720440.4

(22) Date of filing: 06.02.2006
(51) International Patent Classification (IPC): 
C12Q 1/68(2006.01)
(86) International application number:
PCT/US2006/004280
(87) International publication number:
WO 2006/084272 (10.08.2006 Gazette 2006/32)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK YU

(30) Priority: 04.02.2005 US 650365 P

(71) Applicants:
  • Rosetta Inpharmatics LLC.
    Seattle, WA 98109 (US)
  • Merck & Co., Inc.
    Rahway, New Jersey 07065 (US)

(72) Inventors:
  • DEUTSCH, Paul
    Bothell, Washington 98011 (US)
  • FRIEND, Stephen, H
    Philadelphia, Pennsylvania 19118 (US)
  • DAI, Hongyue
    Princeton, New Jersey 08540 (US)

(74) Representative: Jones Day 
Rechtsanwälte, Attorneys-at-Law, Patentanwälte Prinzregentenstraße 11
80538 München
80538 München (DE)

   


(54) METHODS OF PREDICTING CHEMOTHERAPY RESPONSIVENESS IN BREAST CANCER PATIENTS