(19)
(11) EP 1 850 872 A2

(12)

(43) Date of publication:
07.11.2007 Bulletin 2007/45

(21) Application number: 05723386.8

(22) Date of filing: 18.02.2005
(51) International Patent Classification (IPC): 
A61K 39/395(2006.01)
C07K 16/30(2006.01)
(86) International application number:
PCT/US2005/005405
(87) International publication number:
WO 2006/088464 (24.08.2006 Gazette 2006/34)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR LV MK YU

(30) Priority: 15.02.2005 US 58458
15.02.2005 WO PCT/US2005/004739

(71) Applicant: GTC Biotherapeutics, Inc.
Framingham, MA 01702 (US)

(72) Inventors:
  • STROME, Scott, E.
    Rochester, MN 55902 (US)
  • SCHINDLER, Daniel
    Newton Upper Falls, MA 02464 (US)
  • CHEN, Lieping
    Sparks Glencoe, MD 21152 (US)
  • MEADE, Harry
    Newton, MA (US)
  • ECHELARD, Yann
    Jamaica Plain, MA 02130 (US)

(74) Representative: Williams, Gareth Owen 
Marks & Clerk 66-68 Hills Road
Cambridge CB2 1LA
Cambridge CB2 1LA (GB)

   


(54) A METHOD OF USING AN ANTI-CD137 ANTIBODY AS AN AGENT FOR RADIOIMMUNOTHERAPY OR RADIOIMMUNODETECTION