(19)

(11)

EP 1 853 572 A1

(12)

(43) Date of publication: 14.11.2007 Bulletin 2007/46 (21) Application number: 06705147.4 (22) Date of filing: 10.02.2006

(51) International Patent Classification (IPC):  C07D 265/36(2006.01) A61K 31/538(2006.01) A61P 25/16(2006.01) (86) International application number: PCT/CA2006/000191 (87) International publication number: WO 2006/084368 (17.08.2006 Gazette 2006/33)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 14.02.2005 US 651997 P 22.08.2005 US 709801 P (71) Applicant: Clera Inc. Toronto, ON M5P 3L6 (CA)	(72) Inventor: SEEMAN, Philip Toronto, Ontario M4V 2X1 (CA) (74) Representative: Brasnett, Adrian Hugh et al Mewburn Ellis LLP York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)