(19)

(11)

EP 1 853 626 A2

(12)

(88) Date of publication A3: 24.05.2007 (43) Date of publication: 14.11.2007 Bulletin 2007/46 (21) Application number: 06709776.6 (22) Date of filing: 16.02.2006

(51) International Patent Classification (IPC):  C07K 14/47(2006.01) A61K 38/17(2006.01) A61P 25/28(2006.01) G01N 33/68(2006.01) (86) International application number: PCT/GB2006/000539 (87) International publication number: WO 2006/087550 (24.08.2006 Gazette 2006/34)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 18.02.2005 GB 0503434 (71) Applicant: Senexis Limited Cambridge CB2 4AT (GB)	(72) Inventors: DOIG, Andrew Faculty of Life Sciences Sackville Street Manchester M60 1QD (GB) STOTT, Kevin Senexis Limited Cambridge CB2 4AT (GB) TREHERNE, Mark Senexis Limited Cambridge CB2 4AT (GB) SCOPES, David Senexis Limited Cambridge CB2 4AT (GB) (74) Representative: Wakerley, Helen Rachael et al Reddie & Grose 16 Theobalds Road London WC1X 8PL London WC1X 8PL (GB)