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(11)

EP 1 856 137 A1

(12)

(43) Date of publication: 21.11.2007 Bulletin 2007/47 (21) Application number: 05724361.0 (22) Date of filing: 04.03.2005

(51) International Patent Classification (IPC):  C07H 21/04(2006.01) C12N 15/63(2006.01) (86) International application number: PCT/US2005/006796 (87) International publication number: WO 2006/093496 (08.09.2006 Gazette 2006/36)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (71) Applicant: MEDIMMUNE, INC. Gaithersburg, MD 20878 (US)	(72) Inventors: DALL'ACQUA, William Gaithersburg, MD 20878 (US) WU, Herren Boyds, MD 20841 (US) DAMSCHRODER, Melissa Germantown, MD 20874 (US) (74) Representative: Chapman, Paul Gilmour et al Marks & Clerk 19 Royal Exchange Square Glasgow G1 3AE Glasgow G1 3AE (GB)