(19)

(11)

EP 1 856 296 A2

(12)

(88) Date of publication A3: 26.04.2007 (43) Date of publication: 21.11.2007 Bulletin 2007/47 (21) Application number: 06748371.9 (22) Date of filing: 13.03.2006

(51) International Patent Classification (IPC):  C12Q 1/68(2006.01) (86) International application number: PCT/US2006/009016 (87) International publication number: WO 2006/099365 (21.09.2006 Gazette 2006/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 11.03.2005 US 660322 P 24.08.2005 US 711447 P 09.03.2006 US 373834 (71) Applicant: Applera Corporation Rockville, MD 20850 (US)	(72) Inventors: LUKE, May, CELERA GENOMICS Rockville, Maryland 20850 (US) CARGILL, Michele, CELERA GENOMICS Rockville, Maryland 20850 (US) DEVLIN, James, CELERA GENOMICS Rockville, Maryland 20850 (US) SHIFFMAN, Dov, CELERA GENOMICS Rockville, Maryland 20850 (US) (74) Representative: Hermann, Bettina Celia  Jones Day Prinzregentenstraße 11 80538 München 80538 München (DE)