(19)
(11) EP 1 863 512 A1

(12)

(43) Date of publication:
12.12.2007 Bulletin 2007/50

(21) Application number: 06737889.3

(22) Date of filing: 08.03.2006
(51) International Patent Classification (IPC): 
A61K 38/00(2006.01)
(86) International application number:
PCT/US2006/008757
(87) International publication number:
WO 2006/104672 (05.10.2006 Gazette 2006/40)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

(30) Priority: 24.03.2005 US 665646 P
15.09.2005 US 717644 P

(71) Applicant: IRM, LLC
Hamilton, HM 11 (BM)

(72) Inventors:
  • NASOFF, Marc
    San Diego, California 92126 (US)
  • DEVERAUX, Quinn, L.
    San Diego, California 92131 (US)
  • QUON, Kim, C.
    Belmont, California 94002 (US)
  • ROTTMAN, Sabine
    San Diego, California 92122 (US)

(74) Representative: Kiddle, Simon John et al
Mewburn Ellis LLP York House, 23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) ENHANCING MYC-DEPENDENT SENSITIVITY OF CANCER TO DR5 AGONISTS