(19)
(11) EP 1 863 820 A1

(12)

(43) Date of publication:
12.12.2007 Bulletin 2007/50

(21) Application number: 06725220.5

(22) Date of filing: 22.03.2006
(51) International Patent Classification (IPC): 
C07D 491/04(2006.01)
A61P 1/00(2006.01)
 C07D 471/04(2006.01)
A61K 31/4188(2006.01)
(86) International application number:
PCT/EP2006/060936
(87) International publication number:
WO 2006/100255 (28.09.2006 Gazette 2006/39)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK YU

(30) Priority: 24.03.2005 EP 05102407
16.08.2005 EP 05107518

(71) Applicant: Nycomed GmbH
78467 Konstanz (DE)

(72) Inventors:
  • CHIESA, Maria Vittoria
    78464 Konstanz (DE)
  • ZIMMERMANN, Peter Jan
    71139 Ehningen (DE)
  • BUHR, Wilm
    78465 Konstanz (DE)
  • BREHM, Christof
    78462 Konstanz (DE)
  • PALMER, Andreas
    D-78224 Singen (DE)
  • SIMON, Wolfgang-Alexander
    78464 Konstanz (DE)
  • KROMER, Wolfgang
    78464 Konstanz (DE)
  • POSTIUS, Stefan
    78467 Konstanz (DE)
  • HOLST, Hans Christof
    78467 Konstanz (DE)

(74) Representative: Wild, Robert et al
Nycomed GmbH Postfach 10 03 10
78403 Konstanz
78403 Konstanz (DE)

   


(54) THIOAMIDE-SUBSTITUTED TRICYCLIC BENZIMIDAZOLES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISEASES