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EP 1 863 903 A1

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(43) Date of publication: 12.12.2007 Bulletin 2007/50 (21) Application number: 05770085.8 (22) Date of filing: 05.08.2005

(51) International Patent Classification (IPC):  C12N 5/00(2006.01) A61K 35/14(2006.01) A61P 25/28(2006.01) C12N 5/08(2006.01) A61P 25/00(2006.01) (86) International application number: PCT/EP2005/008527 (87) International publication number: WO 2006/102933 (05.10.2006 Gazette 2006/40)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 29.03.2005 RU 2005108721 (71) Applicant: Meditech Industries LLC County of Sussex, Lewes DE 19958 (US)

(72) Inventors: BRYUKHOVETSKIY, Andrei Stepanovich Zheleznodorzhny-Moscow, 143990 (RU) MENTEKEVICH, Georgiy Ludomirovich Moscow, 125499 (RU) MKHEIDZE, Deimuri Melitonovich Moscow, 115446 (RU) YARYGIN, Vladimir Nikitich Moscow, 119021 (RU) ZAITSEV, Andrei Yuryevich Moscow, 125475 (RU) PALUMBO, Olga CH-6816 Bissone (CH) (74) Representative: Long, Giorgio et al Jacobacci & Partners S.p.A. Via Senato, 8 20121 Milano 20121 Milano (IT)