(19)

(11)

EP 1 863 927 A2

(12)

(88) Date of publication A3: 12.04.2007 (43) Date of publication: 12.12.2007 Bulletin 2007/50 (21) Application number: 06725045.6 (22) Date of filing: 14.03.2006

(51) International Patent Classification (IPC):  C12Q 1/68(2006.01) (86) International application number: PCT/EP2006/060693 (87) International publication number: WO 2006/097463 (21.09.2006 Gazette 2006/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 15.03.2005 EP 05290574 17.05.2005 US 681738 P 07.09.2005 EP 05291850 14.09.2005 US 717140 P (71) Applicant: ARES TRADING S.A. 1170 Aubonne (CH)	(72) Inventors: CHUMAKOV, Ilya F-77000 Vaux-le-Penil (FR) COHEN, Daniel F-78110 Le Vesinet (FR) MACCIARDI, Fabio F-75005 Paris (FR) BELLOIR, Benedicte F-91100 Corbeil-Essonnes (FR) (74) Representative: Merck Serono International S.A. Intellectual Property  Intellectual Property Department 9, chemin des Mines 1202 Geneva 1202 Geneva (CH)