(19)

(11)

EP 1 865 896 A1

(12)

(43) Date of publication: 19.12.2007 Bulletin 2007/51 (21) Application number: 06738155.8 (22) Date of filing: 14.03.2006

(51) International Patent Classification (IPC):  A61F 13/00(2006.01) (86) International application number: PCT/US2006/009065 (87) International publication number: WO 2006/099390 (21.09.2006 Gazette 2006/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 14.03.2005 US 661031 P (71) Applicant: MacroChem Corporation Lexington, MA 02421-3134 (US)	(72) Inventor: CHAN, Thomas Hopkinton, Massachusetts 01748 (US) (74) Representative: Lock, Graham James et al Fry Heath & Spence LLP The Gables Massetts Road Horley, Surrey RH6 7DQ Horley, Surrey RH6 7DQ (GB)