(19)
(11) EP 1 865 977 A2

(12)

(43) Date of publication:
19.12.2007 Bulletin 2007/51

(21) Application number: 06738724.1

(22) Date of filing: 17.03.2006
(51) International Patent Classification (IPC): 
A61K 38/08(2006.01)
A61K 38/06(2006.01)
(86) International application number:
PCT/US2006/009695
(87) International publication number:
WO 2006/102068 (28.09.2006 Gazette 2006/39)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK YU

(30) Priority: 17.03.2005 US 84714
19.07.2005 US 186629

(71) Applicants:
  • The Burnham Institute for Medical Research
    La Jolla CA 92037 (US)
  • TORREY PINES INSTITUTE FOR MOLECULAR STUDIES
    San Diego, CA 92121 (US)

(72) Inventors:
  • REED, John, C.
    La Jolla, CA 92037 (US)
  • HOUGHTEN, Rihcard, A.
    San Diego, CA 92121 (US)
  • NEFZI, Adel
    San Diego, CA 92121 (US)
  • OSTRESH, John, M.
    San Diego, CA 92121 (US)
  • PINILLA, Clemencia
    San Diego, CA 92121 (US)
  • WELSH, Kate
    La Jolla, CA 92037 (US)

(74) Representative: UEXKÜLL & STOLBERG 
Patentanwälte Beselerstrasse 4
22607 Hamburg
22607 Hamburg (DE)

   


(54) METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE