(19)

(11)

EP 1 866 277 A2

(12)

(88) Date of publication A3: 11.01.2007 (43) Date of publication: 19.12.2007 Bulletin 2007/51 (21) Application number: 06739439.5 (22) Date of filing: 22.03.2006

(51) International Patent Classification (IPC):  C07C 233/00(2006.01) C07D 211/82(2006.01) A61K 31/16(2006.01) A61K 31/44(2006.01) C07D 211/30(2006.01) C07D 261/06(2006.01) A61K 31/42(2006.01) A61K 31/47(2006.01) (86) International application number: PCT/US2006/010640 (87) International publication number: WO 2006/102535 (28.09.2006 Gazette 2006/39)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 22.03.2005 US 664139 P (71) Applicant: CELERA GENOMICS Rockville, Maryland 20850 (US)	(72) Inventor: MOSSMAN, Craig, J. Campbell, California 95008 (US) (74) Representative: Campbell, Patrick John Henry  J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)