(19)

(11)

EP 1 866 318 A2

(12)

(88) Date of publication A3: 28.12.2006 (43) Date of publication: 19.12.2007 Bulletin 2007/51 (21) Application number: 06737303.5 (22) Date of filing: 02.03.2006

(51) International Patent Classification (IPC):  C07D 495/04(2006.01) A61K 31/4365(2006.01) A61P 7/06(2006.01) (86) International application number: PCT/US2006/008117 (87) International publication number: WO 2006/094292 (08.09.2006 Gazette 2006/36)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 02.03.2005 US 658131 P (71) Applicant: FIBROGEN, INC. South San Francisco, CA 94080 (US)	(72) Inventors: TURTLE, Eric D. Belmont, California 94002 (US) FLIPPIN, Lee A. Woodside, California 94062 (US) AREND, Michael P. Foster City, California 94404 (US) CHENG, Heng Foster City, California 94404 (US) (74) Representative: Goodfellow, Hugh Robin et al Carpmaels & Ransford, 43-45 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)