| (84) |
Designated Contracting States: |
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AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE
SI SK TR |
| (30) |
Priority: |
25.03.2005 US 665322 P
03.06.2005 US 687265 P
|
| (43) |
Date of publication of application: |
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19.12.2007 Bulletin 2007/51 |
| (60) |
Divisional application: |
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10181638.7 / 2343320 |
| (73) |
Proprietor: GITR, Inc. |
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Cambridge, MA 02141 (US) |
|
| (72) |
Inventors: |
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- SMITH, L., Mary
Dedham, Massachusetts 02026 (US)
- SZYMANSKA, Grazyna
Dedham, Massachusetts 02026 (US)
- PONATH, Paul
San Francisco, CA 94114 (US)
- ROSENZWEIG, Michael
Boston, Massachusetts 02118 (US)
- PONTE, Jose, F.
Hanover, MA 02339 (US)
|
| (74) |
Representative: Grund, Martin |
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Grund Intellectual Property Group
Patentanwalt und Solicitor PartG mbB
Postfach 44 05 16
80754 München
80754 München (DE) |
| (56) |
References cited: :
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immunological self-tolerance" NATURE IMMUNOLOGY, NATURE PUBLISHING GROUP,, GB, vol.
3, no. 2, 20 February 2002 (2002-02-20), pages 135-142, XP002247979 ISSN: 1529-2908
cited in the application
- KANAMARU FUMIKO ET AL: "Costimulation via glucocorticoid-induced TNF receptor in both
conventional and CD25+ regulatory CD4+ T cells" JOURNAL OF IMMUNOLOGY, vol. 172, no.
12, 15 June 2004 (2004-06-15), pages 7306-7314, XP009076431 ISSN: 0022-1767
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RECEPTOR FAMILY INHIBITS T CELL RECEPTOR-INDUCED APOPTOSIS" PROCEEDINGS OF THE NATIONAL
ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol.
94, no. 12, June 1997 (1997-06), pages 6216-6221, XP002061244 ISSN: 0027-8424 cited
in the application
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effects on tumor-infiltrating Foxp3(+)CD25(+)CD4(+) regulatory T cells" JOURNAL OF
EXPERIMENTAL MEDICINE, vol. 202, no. 7, October 2005 (2005-10), pages 885-891, XP009076415
ISSN: 0022-1007
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AND ITS RECEPTOR, A HUMAN ORTHOLOG OF MOUSE GITR" CURRENT BIOLOGY, CURRENT SCIENCE,,
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0960-9822
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pages 364-370, XP004215163 ISSN: 0167-5699
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PUBLISHERS BV, NL, vol. 2, no. 3, September 1996 (1996-09), pages 169-179, XP004070292
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ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 21, no. 11, November 2003 (2003-11), pages
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AMSTERDAM, NL, vol. 137, no. 1, 27 December 1993 (1993-12-27), pages 109-118, XP002031537
ISSN: 0378-1119
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