(19)
(11) EP 1 869 048 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
15.04.2009 Bulletin 2009/16

(45) Mention of the grant of the patent:
26.11.2008 Bulletin 2008/48

(21) Application number: 06732122.4

(22) Date of filing: 13.04.2006
(51) International Patent Classification (IPC): 
C07D 475/04(2006.01)
(86) International application number:
PCT/JP2006/308264
(87) International publication number:
WO 2006/112495 (26.10.2006 Gazette 2006/43)

(54)

METHOD FOR PRODUCING ALPHA FORM CRYSTALS OF SAPROPTERIN HYDROCHLORIDE

VERFAHREN ZUR HERSTELLUNG VON ALPHAFORMKRISTALLEN VON SAPROPTERINHYDROCHLORID

PROCEDE DE PRODUCTION DE CRISTAUX DE CHLORHYDRATE DE SAPROPTERINE DE FORME ALPHA

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK YU

(30) Priority: 14.04.2005 JP 2005116687

(43) Date of publication of application:
26.12.2007 Bulletin 2007/52

(73) Proprietors:
  • Shiratori Pharmaceutical Co., Ltd.
    Narashino-shi Chiba 275-0016 (JP)
  • Asubio Pharma Co., Ltd.
    Minato-ku Tokyo 107-8541 (JP)

(72) Inventors:
  • HOTODA, Katsumi
    1340083 (JP)
  • KIYONO, Hiroomi
    2740825 (JP)
  • TAZAWA, Shinnosuke
    2630043 (JP)

(74) Representative: Blodig, Wolfgang 
Wächtershäuser & Hartz Patentanwälte Weinstrasse 8
80333 München
80333 München (DE)


(56) References cited: : 
US-A- 4 713 454
   
  • SCHIRCKS B ET AL: "A NEW, REGIOSPECIFIC SYNTHESIS OF L-BIOPTERIN" HELVETICA CHIMICA ACTA, VERLAG HELVETICA CHIMICA ACTA. BASEL, CH, vol. 68, no. 6, 1985, pages 1639-1643, XP009063871 ISSN: 0018-019X cited in the application
  • B SCHIRCKS ET AL.: HELVETICA CHIMICA ACTA, vol. 61, no. 7, 1978, pages 2731-2738, XP002391645 cited in the application
  • PATENT ABSTRACTS OF JAPAN vol. 1997, no. 10, 31 October 1997 (1997-10-31) & JP 09 157270 A (SHIRATORI SEIYAKU KK; SUNTORY LTD), 17 June 1997 (1997-06-17) cited in the application
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).