(19)

(11)

EP 1 871 768 A1

(12)

(43) Date of publication: 02.01.2008 Bulletin 2008/01 (21) Application number: 06791503.3 (22) Date of filing: 13.04.2006

(51) International Patent Classification (IPC):  C07D 403/12(2006.01) A61P 25/00(2006.01) A61K 31/403(2006.01) (86) International application number: PCT/EP2006/003778 (87) International publication number: WO 2006/136223 (28.12.2006 Gazette 2006/52)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: HR (30) Priority: 15.04.2005 GB 0507680 (71) Applicant: GLAXO GROUP LIMITED Greenford, Middlesex UB6 ONN (GB)	(72) Inventors: HAMPRECHT, Dieter, GlaxoSmithKline I-37135 Verona (IT) MAZZONI, Caterina, GlaxoSmithKline I-37135 Verona (IT) MICHELI, Fabrizio, GlaxoSmithKline I-37135 Verona (IT) (74) Representative: Mauro, Marina Eliana et al GlaxoSmithKline S.p.A. Via A. Fleming, 2 I-37135 Verona I-37135 Verona (IT)