(19)
(11) EP 1 871 808 A2

(12)

(88) Date of publication A3:
29.03.2007

(43) Date of publication:
02.01.2008 Bulletin 2008/01

(21) Application number: 06748967.4

(22) Date of filing: 31.03.2006
(51) International Patent Classification (IPC): 
C07K 16/28(2006.01)
(86) International application number:
PCT/US2006/011752
(87) International publication number:
WO 2006/105338 (05.10.2006 Gazette 2006/40)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

(30) Priority: 31.03.2005 US 667197 P
05.05.2005 US 124620
03.08.2005 US 705378 P
03.10.2005 US 723335 P
03.10.2005 US 723294 P

(71) Applicant: Xencor, Inc.
Monrovia, CA 91016 (US)

(72) Inventors:
  • LAZAR, Gregory, Alan
    Arcadia, CA 91007 (US)
  • DANG, Wei
    Pasadena, CA 91106 (US)
  • DESJARLAIS, John, R.
    Pasadena, CA 91104 (US)
  • KARKI, Sher, Bahadur
    Ponoma, CA 91767 (US)

(74) Representative: Kiddle, Simon John et al
Mewburn Ellis LLP York House, 23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) Fc VARIANTS WITH OPTIMIZED PROPERTIES