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EP 1 874 735 A1

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(43) Date of publication: 09.01.2008 Bulletin 2008/02 (21) Application number: 06743313.6 (22) Date of filing: 18.04.2006

(51) International Patent Classification (IPC):  C07D 235/06(2006.01) A61P 25/00(2006.01) A61K 31/4184(2006.01) (86) International application number: PCT/EP2006/061621 (87) International publication number: WO 2006/111517 (26.10.2006 Gazette 2006/43)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 19.04.2005 DK 200500566 20.04.2005 US 672878 P (71) Applicant: NEUROSEARCH A/S 2750 Ballerup (DK)

(72) Inventors: TEUBER, Lene, DK-3500 Værløse (DK) LARSEN, Janus S., c/o NeuroSearch A/S DK-2750 Ballerup (DK) AHRING, Philip K., c/o NeuroSearch A/S DK-2750 Ballerup (DK) NIELSEN, Elsebet Østergaard, c/o NeuroSearch A/S DK-2750 Ballerup (DK) MIRZA, Naheed, c/o NeuroSearch A/S DK-2750 Ballerup (DK) (74) Representative: Abildgren, Michael Padkjaer et al NeuroSearch A/S Patent Department 93 Pederstrupvej 2750 Ballerup 2750 Ballerup (DK)