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EP 1 874 822 A1

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(43) Date of publication: 09.01.2008 Bulletin 2008/02 (21) Application number: 06735383.9 (22) Date of filing: 15.02.2006

(51) International Patent Classification (IPC):  C07K 16/30(2006.01) A61P 13/00(2006.01) (86) International application number: PCT/US2006/005693 (87) International publication number: WO 2006/112933 (26.10.2006 Gazette 2006/43)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 17.05.2005 WO PCT/US2005/017412 17.05.2005 US 131648 14.04.2005 US 672000 P (71) Applicant: Agensys, Inc. Santa Monica CA 90404 (US)

(72) Inventors: GUDAS, Jean Los Angeles, CA 90049 (US) JAKOBOVITS, Aya Beverly Hills, CA 90210 (US) JIA, Xiao-Chi Los Angeles, CA 90034 (US) MORRISON, Robert, Kendall Santa Monica, CA 90403 (US) CHALLITA-EID, Pia, M. Encino, CA 91436 (US) RAITANO, Arthur, B. Los Angeles, CA 90066 (US) (74) Representative: Irvine, Jonquil Claire  Marks & Clerk 4220 Nash Court Oxford Business Park South Oxford OX4 2RU Oxford OX4 2RU (GB)