MULTI-STEP PROCESS FOR THE MANUFACTURE OF THERAPEUTIC PROTEIN - Patent 1874916

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EP 1 874 916 A2

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(88)	Date of publication A3:
	28.12.2006

(43)	Date of publication:
	09.01.2008 Bulletin 2008/02

(21)	Application number: 06751824.1

(22)	Date of filing: 28.04.2006

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International Patent Classification (IPC):

C12M 3/00^(2006.01)

(86)	International application number:
	PCT/US2006/016334

(87)	International publication number:
	WO 2006/119054 (09.11.2006 Gazette 2006/45)

(84)	Designated Contracting States:
	DE FR GB IT NL

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Priority:

29.04.2005 US 676528 P
29.04.2005 US 676337 P
29.04.2005 US 676129 P
29.04.2005 US 676336 P

(71)	Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
	Wilmington, Delaware 19898 (US)

(72)	Inventors:
	JENKINS, Lauri, Laurene Newark, Delaware 19711 (US) KENNEDY, Jay, Irving Circleville, Ohio 43113 (US) LUSVARDI, Victor, Sisto Chadds Ford, Pennsylvania 19317 (US) SEVERYN, Colleen, Merritt Media, Pennsylvania 19063 (US) BUTLER, Toni, T. Newark, Delaware 19702 (US)

(74)	Representative: Matthews, Derek Peter
	Frank B. Dehn & Co. St Bride's House 10 Salisbury Square London EC4Y 8JD London EC4Y 8JD (GB)

(54)	MULTI-STEP PROCESS FOR THE MANUFACTURE OF THERAPEUTIC PROTEIN