(19)
(11) EP 1 887 358 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
22.02.2012 Bulletin 2012/08

(45) Mention of the grant of the patent:
29.06.2011 Bulletin 2011/26

(21) Application number: 06745768.9

(22) Date of filing: 27.04.2006
(51) International Patent Classification (IPC): 
G01N 33/53(2006.01)
G01N 21/78(2006.01)
 G01N 21/76(2006.01)
G01N 33/543(2006.01)
(86) International application number:
PCT/JP2006/308840
(87) International publication number:
WO 2006/118195 (09.11.2006 Gazette 2006/45)

(54)

METHOD OF IMMUNOLOGICALLY ANALYZING PLASMIN DEGRADATION PRODUCT OF STABILIZED FIBRIN

VERFAHREN ZUR IMMUNOLOGISCHEN ANALYSE VON PLASMINABBAUPRODUKTEN VON STABILISIERTEM FIBRIN

METHODE D'ANALYSE IMMUNOLOGIQUE DU PRODUIT DE DEGRADATION DE LA PLASMINE DE FIBRINE STABILISEE

(84) Designated Contracting States:
DE ES FR GB IT

(30) Priority: 28.04.2005 JP 2005132444

(43) Date of publication of application:
13.02.2008 Bulletin 2008/07

(73) Proprietor: Mitsubishi Chemical Medience Corporation
Tokyo 108-8559 (JP)

(72) Inventor:
  • MATSUYA, Takeshi,
    Tokyo 108-8559 (JP)

(74) Representative: Vossius & Partner 
Siebertstrasse 4
81675 München
81675 München (DE)


(56) References cited: : 
EP-A- 0 347 933
 JP-A- 2003 315 338
   
  • PFIXTZNER S A ET AL: "FIBRIN DETECTED IN PLASMA OF PATIENTS WITH DISSEMINATED INTRAVASCULAR COAGULATION BY FIBRIN-SPECIFIC ANTIBODIES CONSISTS PRIMARILY OF HIGH MOLECULAR WEIGHT FACTOR XIIIA-CROSSLINKED AND PLASMIN-MODIFIED COMPLEXES PARTIALLY CONTAINING FIBRINOPEPTIDE A" THROMBOSIS AND HAEMOSTASIS, STUTTGART, DE, vol. 78, no. 3, 1 September 1997 (1997-09-01), pages 1069-1078, XP002912988 ISSN: 0340-6245
  • VON LODE P: "Point-of-care immunotesting: Approaching the analytical performance of central laboratory methods" CLINICAL BIOCHEMISTRY, ELSEVIER INC, US, CA, [Online] vol. 38, no. 7, 25 April 2005 (2005-04-25), pages 591-606, XP004974179 ISSN: 0009-9120 Retrieved from the Internet: URL:http://www.sciencedirect.com/science?_ ob=ArticleURL&_udi=B6TDD-4G1GD3R-1&_user=9 87766&_rdoc=1&_fmt=&_orig=search&_sort=d&v iew=c&_acct=C000049880&_version=1&_urlVers ion=0&_userid=987766&md5=88f13947450c623f0 bbdee973f3964d7> [retrieved on 2009-02-13]
  • BRONSTEIN I ET AL: "1,2-DIOXETANES: NOVEL CHEMILUMINESCENT ENZYME SUBSTRATES APPLICATIONS TO IMMUNOASSAYS" JOURNAL OF BIOLUMINESCENCE AND CHEMILUMINESCENCE, vol. 4, no. 1, 1989, pages 99-111, XP008102186 & VTH INTERNATIONAL SYMPOSIUM ON BIOLUMINESCENCE AND CHEMILUMINESCENCE, FLORENCE-BOLOGNA, ITALY, SEPTE ISSN: 0884-3996
  • MATSUMOTO TAKESHI ET AL: "Elevated plasma levels of fibrin degradation products by granulocyte-derived elastase (GE-XDP) in patients with disseminated intravascular coagulation (DIC)." BLOOD, vol. 102, no. 11, 16 November 2003 (2003-11-16), page 92b, XP008102160 & 45TH ANNUAL MEETING OF THE AMERICAN SOCIETY OF HEMATOLOGY; SAN DIEGO, CA, USA; DECEMBER 06-09, 2003 ISSN: 0006-4971
  • DEMPFLE C E: "Use of D-dimer assays in the diagnosis of venous thrombosis" SEMINARS IN THROMBOSIS AND HEMOSTASIS, STUTTGART, DE, vol. 26, no. 6, 31 December 2000 (2000-12-31), pages 631-641, XP008085328 ISSN: 0094-6176
  • EGGERDING VENITA C: "Clinical utility of a homogenous D-dimer assay, as compared to two different ELISA assays" BLOOD, vol. 98, no. 11 Part 2, 16 November 2001 (2001-11-16), pages 80b-81b, XP008102120 & 43RD ANNUAL MEETING OF THE AMERICAN SOCIETY OF HEMATOLOGY, PART 2; ORLANDO, FLORIDA, USA; DECEMBER 07-11, 2001 ISSN: 0006-4971
  • STEGNAR M ET AL: "PROGRESSIVE EXPOSURE OF E-NEOANTIGEN ASSOCIATED WITH DEGRADATION OF CROSSLINKED FIBRIN BY PLASMIN IN-VITRO" THROMBOSIS AND HAEMOSTASIS, vol. 52, no. 3, 1984, pages 315-320, XP008102112 ISSN: 0340-6245
  • DEMPFLE: "Validation, calibration, and specificity of quantitative D-dimer assays" SEMINARS IN VASCULAR MEDICINE, vol. 5, no. 4, November 2005 (2005-11), pages 315-320, XP008102098
  • HIMIZU M.: 'LPIA-100 ni Okeru D-Dimer Sokutei no Kisoteki Kento' JAPANESE JOURNAL OF CLINICAL LABORATORY AUTOMATION vol. 16, no. 1, 1991, pages 59 - 63, XP003003324
  • BOUNAMEAUX H.: 'Plasma Measurement of D-Dimer as Diagnostic Aid in Suspected Venous Thromboembolism: An Overview' THROMBOSIS AND HAEMOSTATSIS vol. 71, no. 1, 1994, pages 1 - 6, XP003003325
   
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