(19)
(11) EP 1 908 773 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
09.09.2015 Bulletin 2015/37

(45) Mention of the grant of the patent:
22.07.2015 Bulletin 2015/30

(21) Application number: 08001324.6

(22) Date of filing: 29.12.2003
(51) International Patent Classification (IPC): 
C07K 14/32(2006.01)
C12N 15/52(2006.01)

(54)

Process for producing dipeptides

Verfahren zur Herstellung von Dipeptiden

Procédé de production de dipeptides


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

(30) Priority: 26.12.2002 JP 2002376054
18.12.2003 JP 2003420887

(43) Date of publication of application:
09.04.2008 Bulletin 2008/15

(62) Application number of the earlier application in accordance with Art. 76 EPC:
03029955.6 / 1433791

(73) Proprietor: Kyowa Hakko Bio Co., Ltd.
Tokyo, 100-8185 (JP)

(72) Inventors:
  • Hashimoto, Shin-ichi
    Chiyoda-ku, Tokyo 100-8185 (JP)
  • Tabata, Kazuhiko
    Chiyoda-ku, Tokyo 100-8185 (JP)
  • Hada, Aya
    Tokyo 156-0054 (JP)
  • Ikeda, Hajime
    Chiyoda-ku, Tokyo 100-8185 (JP)

(74) Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB 
Siebertstrasse 3
81675 München
81675 München (DE)


(56) References cited: : 
WO-A-00/03009
   
  • DATABASE UniProt 1 February 1995 (1995-02-01), "Hypothetical protein ywfE" XP002314261 retrieved from EBI Database accession no. P39461
  • DATABASE UniProt 1 October 2002 (2002-10-01), "BacD" XP002314262 retrieved from EBI Database accession no. Q8KWT3
  • YAZGAN ET AL: "Bacilysin biosynthesis by a partially-purified enzyme fraction from Bacillus subtilis" ENZYME AND MICROBIAL TECHNOLOGY, vol. 29, 2001, pages 400-406, XP002314314
  • KHUMTAVEEPORN ET AL: "Expanded structural and stereospecificity in peptide synthesis with chemically modified mutants of subtilisin" TETRAHEDRON ASYMMETRY, vol. 10, 1999, pages 2563-2572, XP004174135
  • TABATA ET AL: "ywfE in Bacillus subtilis codes for a novel enzyme, L-amino acid ligase" JOURNAL OF BACTERIOLOGY, vol. 187, 2005, pages 5195-5202, XP008054400
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).