| (19) |
 |
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(11) |
EP 1 918 974 A3 |
| (12) |
EUROPEAN PATENT APPLICATION |
| (88) |
Date of publication A3: |
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24.03.2010 Bulletin 2010/12 |
| (43) |
Date of publication A2: |
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07.05.2008 Bulletin 2008/19 |
| (22) |
Date of filing: 30.10.2007 |
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| (51) |
International Patent Classification (IPC):
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| (84) |
Designated Contracting States: |
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AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO
SE SI SK TR |
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Designated Extension States: |
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AL BA HR MK RS |
| (30) |
Priority: |
30.10.2006 CN 200610142595
09.05.2007 US 746282
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| (71) |
Applicant: National Sun Yat-Sen University |
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Gushan District, Kaohsiung City 804 (TW) |
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| (72) |
Inventors: |
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- Shiea, Jentaie
Kaohsiung City (TW)
- Yuan, Cheng-Hui
Taipei City (TW)
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| (74) |
Representative: Collin, Jérôme et al |
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Cabinet Régimbeau
20, rue de Chazelles
75847 Paris Cedex 17
75847 Paris Cedex 17 (FR) |
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| |
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| (54) |
Mass spectrometer assembly and method for ambient liquid mass spectrometry |
(57) A mass spectrometer including an electrospray-assisted laser desorption ionization
device, which includes: an electrospray unit including a nozzle; a voltage supplying
member disposed to establish between the nozzle and a receiving unit a potential difference
such that liquid drops of the electrospray medium formed at the nozzle are laden with
charges, and such that the liquid drops are forced to leave the nozzle toward the
receiving unit along a traveling path; a laser desorption unit adapted to irradiate
a sample such that analytes contained in the sample are desorbed to fly along a flying
path which intersects the traveling path so as to enable the analytes to be occluded
in the liquid drops, and such that as a result of dwindling in size of the liquid
drops when moving along the traveling path, charges of the liquid drops will pass
on to the analytes occluded therein to form ionized analytes.