(19)
(11) EP 1 920 786 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
22.02.2012 Bulletin 2012/08

(45) Mention of the grant of the patent:
05.10.2011 Bulletin 2011/40

(21) Application number: 06781503.5

(22) Date of filing: 24.07.2006
(51) International Patent Classification (IPC): 
A61K 49/00(2006.01)
A61K 47/26(2006.01)
A61K 9/16(2006.01)
 A61K 51/12(2006.01)
A61K 9/14(2006.01)
A61K 101/00(2006.01)
(86) International application number:
PCT/JP2006/314591
(87) International publication number:
WO 2007/013409 (01.02.2007 Gazette 2007/05)

(54)

ORAL PREPARATION FOR MEASURING PYRIMIDINE METABOLIC CAPACITY

ORALES PRÄPARAT ZUR MESSUNG DER FÄHIGKEIT PYRIMIDIN ZU METABOLISIEREN

PRÉPARATION ORALE UTILE POUR MESURER LA CAPACITÉ DE MÉTABOLISER LA PYRIMIDINE

(84) Designated Contracting States:
BE CH DE ES FR GB GR IT LI LU NL PT TR

(30) Priority: 25.07.2005 JP 2005214762

(43) Date of publication of application:
14.05.2008 Bulletin 2008/20

(73) Proprietor: OTSUKA PHARMACEUTICAL CO., LTD.
Chiyoda-ku Tokyo 101-8535 (JP)

(72) Inventors:
  • INOUE, Yoshiharu,
    Tokushima-shi, Tokushima 771-0182 (JP)
  • MUKAI, Tadashi,
    Tokushima-shi, Tokushima 771-0182 (JP)

(74) Representative: HOFFMANN EITLE 
Patent- und Rechtsanwälte Arabellastraße 4
81925 München
81925 München (DE)


(56) References cited: : 
EP-A- 1 374 911
WO-A1-2004/087146
JP-A- 03 066 613
 WO-A1-02/072153
JP-A- 02 172 918
JP-B1- 46 026 989
   
  • KUBO H ET AL: "Enhancement of oral bioavailability and pharmacological effect of 1-(3,4- dimethoxyphenyl)-2,3-bis(methoxycarbonyl)- 4-hydroxy-6,7,8- trimethoxynaphthalene (TA-7552), a new hypocholesterolemic agent, by micronization in co-ground mixture with D-mannitol" BIOLOGICAL AND PHARMACEUTICAL BULLETIN 1996 JP, vol. 19, no. 5, 1996, pages 741-747, XP002493448 ISSN: 0918-6158
 
Remarks:
The file contains technical information submitted after the application was filed and not included in this specification
 
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).