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(11)

EP 1 922 319 A2

(12)

(88) Date of publication A3: 10.04.2008 (43) Date of publication: 21.05.2008 Bulletin 2008/21 (21) Application number: 07836794.3 (22) Date of filing: 14.08.2007

(51) International Patent Classification (IPC):  C07D 471/04(2006.01) (86) International application number: PCT/US2007/017956 (87) International publication number: WO 2008/021346 (21.02.2008 Gazette 2008/08)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 14.08.2006 US 837804 P 10.05.2007 US 928745 P 10.05.2007 US 928747 P 15.05.2007 US 930392 P 14.06.2007 US 929126 P 05.07.2007 US 958571 P 10.07.2007 US 929703 P 26.07.2007 US 935094 P 26.07.2007 US 935093 P 07.08.2007 US 963922 P (71) Applicant: Teva Pharmaceutical Industries Ltd. 49131 Petah Tiqva (IL)

(72) Inventor: DOLITKY, Ben-Zion 49651 Petach Tiqva (IL) (74) Representative: Russell, Tim et al D Young & Co 120 Holborn London EC1N 2DY London EC1N 2DY (GB)