(19)
(11) EP 1 926 724 A1

(12)

(43) Date of publication:
04.06.2008 Bulletin 2008/23

(21) Application number: 06803950.2

(22) Date of filing: 20.09.2006
(51) International Patent Classification (IPC): 
C07D 403/06(2006.01)
C07D 401/14(2006.01)
C07D 487/04(2006.01)
A61K 31/501(2006.01)
 C07D 409/14(2006.01)
C07D 405/14(2006.01)
C07D 413/06(2006.01)
A61P 35/00(2006.01)
(86) International application number:
PCT/US2006/036736
(87) International publication number:
WO 2007/035841 (29.03.2007 Gazette 2007/13)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

(30) Priority: 21.09.2005 US 719332 P
04.11.2005 US 734049 P

(71) Applicant: Nereus Pharmaceuticals, Inc.
San Diego, CA 92121 (US)

(72) Inventors:
  • PALLADINO, Michael
    Olivenhain, California 92024 (US)
  • LLOYD, George Kenneth
    Poway, California 92064 (US)
  • HAYASHI, Yoshio
    Ritto, Shiga 520-3031 (JP)

(74) Representative: Neuefeind, Regina 
Maiwald Patentanwalts GmbH Elisenhof Elisenstrasse 3
80335 München
80335 München (DE)

   


(54) ANALOGS OF DEHYDROPHENYLAHISTINS AND THEIR THERAPEUTIC USE