(19)

(11)

EP 1 928 500 A2

(12)

(88) Date of publication A3: 21.06.2007 (43) Date of publication: 11.06.2008 Bulletin 2008/24 (21) Application number: 06836152.6 (22) Date of filing: 27.09.2006

(51) International Patent Classification (IPC):  A61K 45/06(2006.01) A61K 31/7115(2006.01) A61K 31/7125(2006.01) G01N 33/68(2006.01) (86) International application number: PCT/US2006/037987 (87) International publication number: WO 2007/038720 (05.04.2007 Gazette 2007/14)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 27.09.2005 US 720981 P (71) Applicants: Coley Pharmaceutical GmbH 40225 Düsseldorf (DE) Coley Pharmaceutical Group, Inc. Wellesley, MA 02481 (US)	(72) Inventors: JURK, Marion 41540 Dormagen (DE) VOLLMER, Joerg 40591 Duesseldorf (DE) KRIEG, Arthur, M. MA 02482 (US) UHLMANN, Eugen 61479 Glashuetten (DE) NOLL, Bernhard, O. 41468 Neuss (DE) (74) Representative: Jump, Timothy John Simon  Venner Shipley LLP 20 Little Britain London EC1A 7DH London EC1A 7DH (GB)