(19)

(11)

EP 1 928 529 A2

(12)

(88) Date of publication A3: 21.06.2007 (43) Date of publication: 11.06.2008 Bulletin 2008/24 (21) Application number: 06815008.5 (22) Date of filing: 20.09.2006

(51) International Patent Classification (IPC):  A61M 16/00(2006.01) A61B 5/08(2006.01) (86) International application number: PCT/US2006/036594 (87) International publication number: WO 2007/040988 (12.04.2007 Gazette 2007/15)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 30.09.2005 US 240197 (71) Applicant: NEW YORK UNIVERSITY New York, NY 10012 (US)	(72) Inventors: RAPOPORT, David, M. New York, NY 10011 (US) NORMAN, Robert, G. New Windsor, NY 12553 (US) (74) Representative: Kopf, Korbinian Paul  Maiwald Patentanwalts GmbH Elisenhof Elisenstrasse 3 80335 München 80335 München (DE)