(19)

(11)

EP 1 931 359 A2

(12)

(88) Date of publication A3: 28.06.2007 (43) Date of publication: 18.06.2008 Bulletin 2008/25 (21) Application number: 06803558.3 (22) Date of filing: 13.09.2006

(51) International Patent Classification (IPC):  A61K 31/715(2006.01) C07H 15/12(2006.01) (86) International application number: PCT/US2006/035761 (87) International publication number: WO 2007/033292 (22.03.2007 Gazette 2007/12)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 14.09.2005 US 717536 P (71) Applicant: Elixir Pharmaceuticals, Inc. Cambridge, MA 02139 (US)	(72) Inventors: WATSON, Alan Lexington, Massachusetts 02420 (US) BRASS, Laura Cambridge, Massachusetts 02139 (US) GEESAMAN, Bard, J. Boston, Massachusetts 02116 (US) KAILIAN, Vaughn Bodega, California 94922 (US) (74) Representative: Williams, Gareth Owen et al Marks & Clerk 62-68 Hills Road Cambridge CB2 1LA Cambridge CB2 1LA (GB)