(19)

(11)

EP 1 933 874 A2

(12)

(88) Date of publication A3: 15.11.2007 (43) Date of publication: 25.06.2008 Bulletin 2008/26 (21) Application number: 06825629.6 (22) Date of filing: 10.10.2006

(51) International Patent Classification (IPC):  A61K 39/40(2006.01) C07K 16/12(2006.01) (86) International application number: PCT/US2006/039361 (87) International publication number: WO 2007/047189 (26.04.2007 Gazette 2007/17)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 11.10.2005 US 725180 P (71) Applicants: IOGENETICS, LLC Madison, WI 53704 (US) Arizona Board of Regents on behalf of the University of Arizona Tucson, AZ 85721-0158 (US)	(72) Inventors: IMBODEN, Michael Madison, WI 53711 (US) RIGGS, Michael, W. Tucson, AZ 85718 (US) SCHAEFER, Deborah Tucson, AZ 85719 (US) (74) Representative: Glawe, Delfs, Moll  Patent- und Rechtsanwälte, Rothenbaumchaussee 58 20148 Hamburg 20148 Hamburg (DE)