(19)

(11)

EP 1 937 242 A2

(12)

(88) Date of publication A3: 05.07.2007 (43) Date of publication: 02.07.2008 Bulletin 2008/27 (21) Application number: 06826134.6 (22) Date of filing: 17.10.2006

(51) International Patent Classification (IPC):  A61K 31/195(2006.01) A61K 31/18(2006.01) A61K 31/505(2006.01) (86) International application number: PCT/US2006/040598 (87) International publication number: WO 2007/047698 (26.04.2007 Gazette 2007/17)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 17.10.2005 US 727564 P 17.10.2005 US 727318 P 17.10.2005 US 251724 13.10.2006 US 549274 (71) Applicant: NeuroTherapeutics Pharma, Inc. Seattle, WA 98102 (US)	(72) Inventors: HOCHMAN, Daryl, W. Bahama, NC 27503 (US) PARTRIDGE, John, J. Chapel Hill, NC 27514 (US) (74) Representative: Campbell, Patrick John Henry et al J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)