(19)
(11) EP 1 937 640 A2

(12)

(88) Date of publication A3:
07.06.2007

(43) Date of publication:
02.07.2008 Bulletin 2008/27

(21) Application number: 06815371.7

(22) Date of filing: 25.09.2006
(51) International Patent Classification (IPC): 
C07D 215/22(2006.01)
A61P 3/10(2006.01)
A61P 9/10(2006.01)
 A61K 31/473(2006.01)
A61P 3/06(2006.01)
A61P 29/00(2006.01)
(86) International application number:
PCT/US2006/037321
(87) International publication number:
WO 2007/041076 (12.04.2007 Gazette 2007/15)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

(30) Priority: 30.09.2005 US 722507 P

(71) Applicant: Janssen Pharmaceutica NV
2340 Beerse (BE)

(72) Inventors:
  • BHARAT, Lagu
    Hillsborough, NJ 08844 (US)
  • PIO, Barbara
    Hillsborough, NJ 08844 (US)

(74) Representative: Warner, James Alexander et al
Carpmaels & Ransford 43-45 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) 1,2,3,5-TETRAHYDRO-CYCLOPENTAL[C]QUINOLIN-4-ONE DERIVATIVES AS RXR AGONISTS FOR THE TREATMENT OF DYSLIPIDEMIA, HYPERCHOLESTEROLEMIA AND DIABETES