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EP 1 937 647 A1

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(43) Date of publication: 02.07.2008 Bulletin 2008/27 (21) Application number: 06779567.4 (22) Date of filing: 28.09.2006

(51) International Patent Classification (IPC):  C07D 231/56(2006.01) A61K 31/416(2006.01) A61P 3/00(2006.01) C07D 471/04(2006.01) A61K 31/437(2006.01) (86) International application number: PCT/GB2006/003608 (87) International publication number: WO 2007/036727 (05.04.2007 Gazette 2007/14)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 29.09.2005 GB 0519874 21.07.2006 GB 0614578 (71) Applicant: Inpharmatica Limited London WC1A 1NU (GB)	(72) Inventors: AYSCOUGH, Andrew Witchford, Ely CB6 2HT (GB) THOMPSON, Stephen Cottenham, Cambridge CB4 8XT (GB) TAYLOR, Susanne Cambridge CB1 3DS (GB) KHAN, Nawaz, Mohammed Hardwick, Cambridge CB3 7QN (GB) (74) Representative: Warner, James Alexander et al Carpmaels & Ransford 43 -45 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)