(19)

(11)

EP 1 940 308 A2

(12)

(88) Date of publication A3: 27.09.2007 (43) Date of publication: 09.07.2008 Bulletin 2008/28 (21) Application number: 06794883.6 (22) Date of filing: 23.10.2006

(51) International Patent Classification (IPC):  A61B 19/00(2006.01) (86) International application number: PCT/GB2006/003947 (87) International publication number: WO 2007/045913 (26.04.2007 Gazette 2007/17)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 22.10.2005 GB 0521536 (71) Applicant: Invibio Limited Lancashire FY5 4QD (GB)	(72) Inventors: DE LANGEN, Mark NL-3075 EA Rotterdam (NL) GREEN, Stuart Preston PR2 5BG (GB) SCHLEGEL, Jorge 72458 Albstadt (DE) (74) Representative: Brierley, Anthony Paul  Appleyard Lees 15 Clare Road Halifax West Yorkshire HX1 2HY Halifax West Yorkshire HX1 2HY (GB)