(19)
(11) EP 1 941 269 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
30.12.2015 Bulletin 2015/53

(45) Mention of the grant of the patent:
21.10.2015 Bulletin 2015/43

(21) Application number: 06813046.7

(22) Date of filing: 25.10.2006
(51) International Patent Classification (IPC): 
G01N 33/543(2006.01)
G01N 30/02(2006.01)
 G01N 30/88(2006.01)
(86) International application number:
PCT/SE2006/050419
(87) International publication number:
WO 2007/050032 (03.05.2007 Gazette 2007/18)

(54)

A METHOD OF SCREENING A BIOLOGICAL TARGET FOR WEAK INTERACTIONS USING WEAK AFFINITY CHROMATOGRAPHY

VERFAHREN ZUM SCREENING EINES BIOLOGISCHEN ZIELS AUF SCHWACHE WECHSELWIRKUNGEN UNTER VERWENDUNG SCHWACHER AFFINITÄTSCHROMATOGRAPHIE

METHODE DE CRIBLAGE D'INTERACTIONS FAIBLES DANS UNE CIBLE BIOLOGIQUE, FAISANT APPEL A UNE CHROMATOGRAPHIE D'AFFINITE FAIBLE

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

(30) Priority: 27.10.2005 US 730808 P

(43) Date of publication of application:
09.07.2008 Bulletin 2008/28

(73) Proprietor: Transientic Interactions AB
193 33 Sigtuna (SE)

(72) Inventors:
  • OHLSON, Sten
    S-211 16 Malmö (SE)
  • SHORAVI, Siamak
    S-393 50 Kalmar (SE)
  • FEX, Tomas
    S-226 52 Lund (SE)
  • ISAKSSON, Roland
    S-224 71 Lund (SE)

(74) Representative: Holmberg, Martin Tor 
Bergenstrahle & Lindvall AB P.O. Box 17704
118 93 Stockholm
118 93 Stockholm (SE)


(56) References cited: : 
EP-A- 0 290 406
 WO-A1-91/12820
   
  • OHLSON S ET AL: "Use of monoclonal antibodies for weak affinity chromatography" JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 758, no. 2, 17 January 1997 (1997-01-17), pages 199-208, XP004034191 ISSN: 0021-9673
  • LEICKT L ET AL: "Affinity screening for weak monoclonal antibodies" JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 220, no. 1-2, 1 November 1998 (1998-11-01), pages 19-24, XP004144098 ISSN: 0022-1759
  • SARASWAT L D ET AL: "Affinity Ligand Selection from a Small Molecules: Assay Development Screening, and Application" BIOTECHNOLOGY PROGRESS, AMERICAN INSTITUTE OF CHEMICAL ENGINEERS, US, vol. 21, no. 1, 1 January 2005 (2005-01-01), pages 300-308, XP003009335 ISSN: 8756-7938
  • LEICKT L. ET AL.: 'Affinity screening for weak monoclonal antibodies' JOURNAL OF IMMUNOLOGICAL METHODS vol. 220, 1998, pages 19 - 24, XP004144098
  • SARASWAT L.D. ET AL.: 'Affinity Ligand Selection from a Small Molecules: Assay Development Screening, and Application' BIOTECHNOL. PROG. vol. 21, 2005, pages 300 - 308, XP003009335
  • OHLSON S. ET AL.: 'Screening for transient biological interactions as applied to albumin ligands: A new concept for drug discovery' ANALYTICAL BIOCHEMISTRY vol. 359, 2006, pages 120 - 123, XP005723847
  • OHLSON S. ET AL.: 'Novel Approach to Affinity Chromatography Using Weak' ANALYTICAL BIOCHEMISTRY vol. 169, 1988, pages 204 - 208, XP003009336
  • ZOPF D. ET AL.: 'Weak-affinity chromatography' NATURE vol. 346, 05 July 1990, pages 87 - 88, XP003009337
  • Strandh, Magnus: "Insights into Weak Affinity Antibody-Antigen Interactions", , 2000, Retrieved from the Internet: URL:http://www.immun.lth.se/fileadmin/immu n/Avhandlingar/Magnus_Strandh.pdf [retrieved on 2012-05-25]
 
Remarks:
The file contains technical information submitted after the application was filed and not included in this specification
 
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).