5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS

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EP 1 943 219 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	07.03.2012 Bulletin 2012/10

(45)	Mention of the grant of the patent:
	26.10.2011 Bulletin 2011/43

(21)	Application number: 06836773.9

(22)	Date of filing: 30.10.2006

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International Patent Classification (IPC):

C07D 209/00^(2006.01)
C07D 403/10^(2006.01)

A61K 31/415^(2006.01)
C07D 471/04^(2006.01)

(86)	International application number:
	PCT/US2006/042690

(87)	International publication number:
	WO 2007/056021 (18.05.2007 Gazette 2007/20)

(54)	5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS HEMMER DES 5-LIPOXYGENASE AKTIVIERENDEN PROTEINS (FLAP) INHIBITEURS DE LA PROTEINE D'ACTIVATION DE LA 5-LIPOXYGENASE (FLAP)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
	Designated Extension States:
	AL BA HR MK RS

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Priority:

04.11.2005 US 734030 P
12.05.2006 US 747174 P
23.08.2006 US 823344 P
27.10.2006 US 553946

(43)	Date of publication of application:
	16.07.2008 Bulletin 2008/29

(60)	Divisional application:
	11171816.9 / 2404904

(73)	Proprietor: Panmira Pharmaceuticals, LLC
	San Diego, CA 92121 (US)

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Inventors:

HUTCHINSON, John, H.
La Jolla, CA 92037 (US)
PRASIT, Petpiboon, Peppi
San Diego, CA 92121 (US)
MORAN, Mark
Orinda, CA 94563 (US)
EVANS, Jillian, F.
San Diego, California 92131 (US)
STEARNS, Brian, Andrew
San Diego, CA 92104 (US)
ROPPE, Jeffrey, Roger
Temecula, CA 92592 (US)
LI, Yiwei
Lower Gwynedd, Pennsylvania 19002 (US)
ZUNIC, Jasmine, Eleanor
San Diego, CA 92127 (US)
ARRUDA, Jeannie, M.
San Diego, California 92104 (US)
STOCK, Nicholas, Simon
San Diego, CA 92111 (US)
HADDACH, Mustapha
San Diego, CA 92127 (US)

(74)	Representative: Price, Susanna Clare Hopley et al
	GlaxoSmithKline Corporate Intellectual Property (CN925.1) 980 Great West Road Brentford, Middlesex TW8 9GS Brentford, Middlesex TW8 9GS (GB)

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References cited: :

WO-A1-93/16069
US-A- 5 081 138
US-A1- 2004 198 800

WO-A2-2004/017917
US-A- 5 204 344

MILLER D.K. ET AL.: 'Identification and isolation of a membrane protein necessary for leukotriene production' NATURE vol. 343, 18 January 1990, pages 278 - 281, XP003015233
ROUZERT C.A. ET AL.: 'MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane associated of 5-Lipooxygenase in Ionophore-challenged' LEUKOCYTES 21 July 1989, XP008127006

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).