(19)

(11)

EP 1 948 144 A2

(12)

(88) Date of publication A3: 20.03.2008 (43) Date of publication: 30.07.2008 Bulletin 2008/31 (21) Application number: 06806712.3 (22) Date of filing: 09.11.2006

(51) International Patent Classification (IPC):  A61K 31/00(2006.01) A61P 3/10(2006.01) A61K 31/4412(2006.01) A61K 31/616(2006.01) A61P 25/02(2006.01) (86) International application number: PCT/EP2006/010747 (87) International publication number: WO 2007/054303 (18.05.2007 Gazette 2007/20)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 10.11.2005 EP 05024507 15.12.2005 EP 05027448 (71) Applicant: Bayer HealthCare AG 51368 Leverkusen (DE)	(72) Inventors: WEBER, Olaf 42489 Wülfrath (DE) RIEDL, Bernd 42329 Wuppertal (DE)