(19)

(11)

EP 1 951 050 A2

(12)

(88) Date of publication A3: 29.11.2007 (43) Date of publication: 06.08.2008 Bulletin 2008/32 (21) Application number: 06817334.3 (22) Date of filing: 25.10.2006

(51) International Patent Classification (IPC):  A01N 43/62(2006.01) A61K 31/44(2006.01) (86) International application number: PCT/US2006/041446 (87) International publication number: WO 2007/050587 (03.05.2007 Gazette 2007/18)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 26.10.2005 US 730711 P (71) Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN Ann Arbor, Michigan 48109 (US)	(72) Inventors: GLICK, Gary, D. Ann Arbor, MI 48103 (US) ROUSH, William R. North Palm Beach, FL 33410 (US) (74) Representative: Glawe, Delfs, Moll  Patent- und Rechtsanwälte, Rothenbaumchaussee 58 20148 Hamburg 20148 Hamburg (DE)