SUBSTITUTED QUINOLONES AND METHODS OF USE

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EP 1 954 274 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	12.01.2011 Bulletin 2011/02

(45)	Mention of the grant of the patent:
	03.11.2010 Bulletin 2010/44

(21)	Application number: 06844355.5

(22)	Date of filing: 13.11.2006

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International Patent Classification (IPC):

C07D 491/056^(2006.01)
C07D 471/04^(2006.01)
A61K 31/455^(2006.01)

C07D 215/233^(2006.01)
A61P 35/00^(2006.01)

(86)	International application number:
	PCT/US2006/044149

(87)	International publication number:
	WO 2007/059108 (24.05.2007 Gazette 2007/21)

(54)	SUBSTITUTED QUINOLONES AND METHODS OF USE SUBSTITUIERTE CHINOLONE UND VERWENDUNGSVERFAHREN QUINOLONES SUBSTITUEES ET PROCEDES D'UTILISATION

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB IE IT LI NL SE

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Priority:

10.11.2005 US 735692 P

(43)	Date of publication of application:
	13.08.2008 Bulletin 2008/33

(60)	Divisional application:
	10013268.7

(73)	Proprietor: ChemoCentryx, Inc.
	Mountain View California 94043 (US)

(72)	Inventors:
	MELIKIAN, Anita San Francisco, California 94114 (US) WRIGHT, John Jessen Sandringam, VIC, 3191 (AU) KRASINSKI, Antoni Mountain View, California 94043 (US) HU, Cheng Menlo Park, California 94025 (US) NOVACK, Aaron San Jose, California 95134 (US)

(74)	Representative: Campbell, Patrick John Henry
	J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)

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References cited: :

WO-A-2004/014859
US-A- 5 126 352
US-A1- 2004 170 634

WO-A1-2004/083207
US-A- 5 753 666
US-B2- 6 677 351

DATABASE CHEMCATS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; (RN: 866727-30-2) 4 November 2005 (2005-11-04), XP007905982 & "Ryan Scientific Screening Library" 25 January 2008 (2008-01-25), RYAN-SCIENTIFIC, INC. , MT. PLEASANR, SC, 29465, USA
VALES M ET AL: "Enaminones acylation: Competitive formation of quinolin-4-one and isoquinolin-1-one derivatives" SYNTHESIS 2001 DE, no. 16, 2001, pages 2419-2426, XP002500053 ISSN: 0039-7881
SILIN ET AL: "Synthesis of 5H-pyrazol[4,3-c]quinolines" HETEROCYCLES, vol. 63, no. 8, 2004, pages 1883-1890, XP008097658
SANDISON ET AL: "A New Heterocyclisation Reaction Leading to Cinnolin-4(1H)-one Derivatives" J.C.S. CHEM. COMM., no. 18, 1974, pages 752-753, XP008097682
OLIPHANT CATHERINE M ET AL: "Quinolones: a comprehensive review." AMERICAN FAMILY PHYSICIAN, vol. 65, no. 3, 1 February 2002 (2002-02-01), pages 455-464, XP007905992 ISSN: 0002-838X

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).