(19)

(11)

EP 1 957 138 A2

(12)

(88) Date of publication A3: 22.11.2007 (43) Date of publication: 20.08.2008 Bulletin 2008/34 (21) Application number: 06839996.3 (22) Date of filing: 22.11.2006

(51) International Patent Classification (IPC):  A61M 15/00(2006.01) A61M 15/08(2006.01) (86) International application number: PCT/US2006/061190 (87) International publication number: WO 2007/067855 (14.06.2007 Gazette 2007/24)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 06.12.2005 US 559372 07.12.2005 US 296637 21.04.2006 US 408906 (71) Applicant: Airpharma L.L.C. Overland Park, KS 66204 (US)

(72) Inventors: PRICE, Robert Chepstow Monmouthshire NP16 6LW (GB) STANIFORTH, John, Nicholas Bath Avon BA2 2AT (GB) WOODCOCK, Derek, Alan Berkhampstead Hertfordshire HP4 3HX (GB) YOUNG, Paul, Michael Bath Avon BA1 1OL (GB) BYRNES, James, A. Overland Park, Kansas 66211 (US) COGBURN, J., Nita Overland Park, Kansas 66211 (US) DOCKHORN, Douglas, R. Overland Park, Kansas 66211 (US) DOCKHORN, Robert, J. Overland Park, Kansas 66211 (US) MITCHELL, Edgar, W. Overland Park, Kansas 66211 (US) PRATHER, Susan, J. Overland Park, Kansas 66211 (US) (74) Representative: Peel, James Peter  Barker Brettell LLP 10-12 Priests Bridge GB-London SW15 5JE GB-London SW15 5JE (GB)