(19)

(11)

EP 1 957 534 A1

(12)

(43) Date of publication: 20.08.2008 Bulletin 2008/34 (21) Application number: 06805553.2 (22) Date of filing: 08.11.2006

(51) International Patent Classification (IPC):  C07K 16/18(2006.01) C07K 14/47(2006.01) A61K 39/00(2006.01) (86) International application number: PCT/DK2006/000614 (87) International publication number: WO 2007/054090 (18.05.2007 Gazette 2007/20)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 09.11.2005 DK 200501556 09.11.2005 US 734747 P (71) Applicant: Pharmexa A/S 2970 Horsholm (DK)	(72) Inventors: BRATT, Tomas DK-2970 Hørsholm (DK) DEGAN, Florence, Dal DK-2970 Hørsholm (DK) NIELSEN, Katja Bergholdt DK-2970 Hørsholm (DK) VOLDBORG, Bjørn DK-2970 Hørsholm (DK) HOLMBERG, Jens DK-2970 Hørsholm (DK) (74) Representative: Inspicos A/S  Bøge Allé 5 P.O. Box 45 2970 Hørsholm 2970 Hørsholm (DK)