(19)
(11) EP 1 967 854 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
29.12.2010 Bulletin 2010/52

(45) Mention of the grant of the patent:
03.11.2010 Bulletin 2010/44

(21) Application number: 07004574.5

(22) Date of filing: 06.03.2007
(51) International Patent Classification (IPC): 
G01N 33/50(2006.01)

(54)

Method for determining the amount of conjugated taxane in polyglutamic acid-taxane conjugates

Verfahren zur Bestimmung der Menge konjugierten Taxans in Polyglutaminsäure-Taxan-Konjugaten

Procédé pour la détermination de la quantité de taxane conjugué dans des conjugués de taxane-acide polyglutamique

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

(43) Date of publication of application:
10.09.2008 Bulletin 2008/37

(73) Proprietor: Cell Therapeutics, Inc.
Seattle (US)

(72) Inventors:
  • Fazioni, Stefano
    20036 Meda (MI) (IT)
  • Hovda, Keith
    Ken, WA 98032 (US)
  • Livi, Valeria
    20099 Sesto San Giovanni (MI) (IT)
  • McKennon, Marc
    Seattle, WA 98107 (US)
  • Siviero, Luigi
    20059 Vimercate (MI) (IT)
  • Spoonemore, Holly
    Bellevue, WA 98006 (US)

(74) Representative: Minoja, Fabrizio 
Bianchetti Bracco Minoja S.r.l. Via Plinio 63
20129 Milano
20129 Milano (IT)


(56) References cited: : 
WO-A-03/004482
 US-B1- 6 281 368
   
  • SHAFFER SCOTT A ET AL: "In vitro and in vivo metabolism of paclitaxel poliglumex: identification of metabolites and active proteases" CANCER CHEMOTHERAPY AND PHARMACOLOGY, vol. 59, no. 4, 19 August 2006 (2006-08-19), pages 537-548, XP002437705 ISSN: 0344-5704
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).