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(11)

EP 1 973 943 A1

(12)

(43) Date of publication: 01.10.2008 Bulletin 2008/40 (21) Application number: 07703694.5 (22) Date of filing: 08.01.2007

(51) International Patent Classification (IPC):  C07K 14/54(2006.01) C07K 14/47(2006.01) C07K 16/24(2006.01) (86) International application number: PCT/EP2007/050143 (87) International publication number: WO 2007/077261 (12.07.2007 Gazette 2007/28)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 06.01.2006 WO PCT/EP2006/050060 09.10.2006 US 539851 (71) Applicant: Topotarget Switzerland SA 1004 Lausanne (CH)	(72) Inventors: PETRILLI, Virginie 1004 Lausanne (CH) MARTINON, Fabio 1004 Lausanne (CH) TSCHOPP, Jurg 1066 Epalinges (CH) DE SMEDT, Thibault 1095 Lutry (CH) (74) Representative: Tetaz, Franck Claude Edouard et al Cabinet Régimbeau 20, rue de Chazelles 75847 Paris Cedex 17 75847 Paris Cedex 17 (FR)