(19)

(11)

EP 1 976 493 A2

(12)

(88) Date of publication A3: 06.12.2007 (43) Date of publication: 08.10.2008 Bulletin 2008/41 (21) Application number: 07716522.3 (22) Date of filing: 11.01.2007

(51) International Patent Classification (IPC):  A61K 9/44(2006.01) A61K 9/70(2006.01) (86) International application number: PCT/US2007/000693 (87) International publication number: WO 2007/084313 (26.07.2007 Gazette 2007/30)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 17.01.2006 US 333602 (71) Applicant: Harrogate Holdings Hamilton, Bermuda HM12 (BM)	(72) Inventor: ROYDS, Robert, B. Plainsboro, NJ 08536 (US) (74) Representative: Loven, Keith James  Loven Patents & Trademarks West Central Runcorn Road Lincoln LN6 3QP Lincoln LN6 3QP (GB)