(19)

(11)

EP 1 976 535 A2

(12)

(88) Date of publication A3: 18.10.2007 (43) Date of publication: 08.10.2008 Bulletin 2008/41 (21) Application number: 07717366.4 (22) Date of filing: 23.01.2007

(51) International Patent Classification (IPC):  A61K 31/66(2006.01) A61P 11/00(2006.01) A61K 38/17(2006.01) (86) International application number: PCT/US2007/060902 (87) International publication number: WO 2007/087524 (02.08.2007 Gazette 2007/31)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 23.01.2006 US 761250 P 23.01.2006 WO PCT/US2006/002423 (71) Applicant: Ony, Inc. Amherst, NY 14228 (US)	(72) Inventors: EGAN, Edmund, A. Buffalo, NY 14226 (US) HOLM, Bruce Buffalo, NY 14610 (US) (74) Representative: Waldren, Robin Michael et al Marks & Clerk 90 Long Acre London WC2E 9RA London WC2E 9RA (GB)