(19)
(11) EP 1 979 466 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
24.10.2012 Bulletin 2012/43

(45) Mention of the grant of the patent:
19.09.2012 Bulletin 2012/38

(21) Application number: 06849257.8

(22) Date of filing: 20.12.2006
(51) International Patent Classification (IPC): 
G01N 33/50(2006.01)
C12M 3/00(2006.01)
C12N 5/00(2006.01)
 C12M 3/04(2006.01)
C12M 1/12(2006.01)
B01L 3/00(2006.01)
(86) International application number:
PCT/US2006/049082
(87) International publication number:
WO 2007/081543 (19.07.2007 Gazette 2007/29)

(54)

HIGH-THROUGHPUT CELL-BASED ASSAYS FABRICATED WITH INTEGRATED SILICON AND CELL CULTURE TECHNOLOGIES

MIT INTEGRIERTEN SILIZIUM- UND ZELLKULTURTECHNIKEN ERZEUGTE TESTVERFAHREN AUF ZELLBASIS MIT HOHEM DURCHSATZ

ANALYSES A BASE DE CELLULES A HAUT RENDEMENT AVEC SILICIUM INTEGRE ET TECHNOLOGIES DE CULTURE CELLULAIRE

(84) Designated Contracting States:
DE FR GB

(30) Priority: 04.01.2006 US 325609

(43) Date of publication of application:
15.10.2008 Bulletin 2008/42

(60) Divisional application:
10191507.2 / 2295532

(73) Proprietor: Agency for Science, Technology and Research
Singapore 138632 (SG)

(72) Inventors:
  • KAN, Shyi-herng
    Singapore 138669 (SG)
  • YING, Jackie, Y.
    Singapore 138669 (SG)
  • YU, Hanry
    Singapore 138669 (SG)
  • SCHUMACHER, Karl
    Singapore 138669 (SG)
  • NG, Susanne, San San
    Singapore 138669 (SG)
  • SUN, Wanxin
    Singapore 138669 (SG)

(74) Representative: HOFFMANN EITLE 
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München
81925 München (DE)


(56) References cited: : 
WO-A-2005/108547
US-A1- 2004 219 184
 US-A1- 2004 067 546
   
  • MA SARINA HARRIS ET AL: "An endothelial and astrocyte co-culture model of the blood-brain barrier utilizing an ultra-thin, nanofabricated silicon nitride membrane." LAB ON A CHIP JAN 2005, vol. 5, no. 1, January 2005 (2005-01), pages 74-85, XP002437850 ISSN: 1473-0197
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).