(19)

(11)

EP 1 981 514 A2

(12)

(88) Date of publication A3: 29.11.2007 (43) Date of publication: 22.10.2008 Bulletin 2008/43 (21) Application number: 07718197.2 (22) Date of filing: 12.01.2007

(51) International Patent Classification (IPC):  A61K 33/42(2006.01) (86) International application number: PCT/US2007/060505 (87) International publication number: WO 2007/084858 (26.07.2007 Gazette 2007/30)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 12.01.2006 US 758207 P (71) Applicant: Rutgers, The State University of New Jersey New Brunswick, NJ 08909 (US)	(72) Inventors: RIMAN, Richard, E. Belle Mead, NJ 08502 (US) SEVER, Christina Somerset, NJ 08873 (US) (74) Representative: Schmidt, Karsten et al Albihns GmbH Bayerstrasse 83 80335 München 80335 München (DE)