(19)

(11)

EP 1 986 626 A1

(12)

(43) Date of publication: 05.11.2008 Bulletin 2008/45 (21) Application number: 07750583.2 (22) Date of filing: 12.02.2007

(51) International Patent Classification (IPC):  A61K 31/196(2006.01) A61P 31/16(2006.01) (86) International application number: PCT/US2007/003755 (87) International publication number: WO 2007/095218 (23.08.2007 Gazette 2007/34)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 13.02.2006 US 772748 P 12.04.2006 WO PCT/US2006/013535 (71) Applicant: BIOCRYST PHARMACEUTICALS INC. Birmingham, Alabama 35244 (US)	(72) Inventors: BABU, Yarlagadda, Sudhakara Birmingham, AL 35226 (US) CHAND, Pooran Birmingham, AL 35226 (US) BANTIA, Shanta Birmingham, AL 35242 (US) ARNOLD, Shane Hoover, AL 35226 (US) KILPATRICK, John, Michael Helena, AL 35080 (US) (74) Representative: Kihn, Pierre Emile Joseph et al Office Ernest T. Freylinger S.A. 234, route d'Arlon B.P. 48 8001 Strassen 8001 Strassen (LU)