(19)

(11)

EP 1 987 139 A2

(12)

(88) Date of publication A3: 28.08.2008 (43) Date of publication: 05.11.2008 Bulletin 2008/45 (21) Application number: 07703378.5 (22) Date of filing: 06.02.2007

(51) International Patent Classification (IPC):  C12N 9/02(2006.01) C12N 15/63(2006.01) C07K 16/40(2006.01) A23C 9/12(2006.01) C12N 15/53(2006.01) C12P 21/02(2006.01) A21D 8/04(2006.01) (86) International application number: PCT/EP2007/001134 (87) International publication number: WO 2007/090675 (16.08.2007 Gazette 2007/33)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 06.02.2006 WO PCT/EP2006/050700 (71) Applicant: DSM IP Assets B.V. 6411 TE Heerlen (NL)	(72) Inventors: MUTSAERS, Johanna Henrica Gerdina Maria NL-2635 GT DEN HOORN (NL) MEIMA, Roelf Bernhard NL-3471 AH Kamerik (NL) VAN DIJK, Albertus Alard P. O. Box 1 NL-2600 MA Delft (NL) DEKKER, Petrus Jacobus Theodorus NL-2497 AE Den Haag (NL) (74) Representative: Monaco, Vania et al DSM Intellectual Property Delft Office 600-0240 P.O. Box 1 2600 MA Delft 2600 MA Delft (NL)